Yea, pro killing is a lot harder than in MNC, tho I think the Pros still need a good bit of balancing work done
I got 250+ hours in SMNC and my advice is: Kill bots, avoid players(especially if the number above their head is yellow/red)
If you are gonna pick a fight, make sure the fight is on your terms. Let the enemy come to you(or make them if you opt to run Veteran) and keep teammates nearby.
A 1 to 2 level advantage isn't going to mean much if the fight is 1 vs 2+
Annihilator also got a massive change. Instead of a "slap the button" mechanic, there's a whole new animation to it and you can get knocked out of it fairly easily
If your team is taking the Anni, block as much incoming fire as possible. Intercept projectiles/grapples, play human shield, etc
If you think your team won't be able to take the Anni, push the botlanes as far as possible and spawn bots right after the lightning hits